May 09, 2022

Related Beal & Jamestown Lease More Than 260,000 SF to Life Science Firms at Boston’s Innovation And Design Building

Diverse group of biotech companies to bring more than 700 jobs to Boston’s Eastern Seaport Neighborhood

The Innovation and Design Building facade with trees in foreground

BOSTON, MA – May 9, 2022 – Related Beal and Jamestown today announced more than 260,000 square feet of life science leasing at the Innovation and Design Building (The IDB) located within the Raymond L. Flynn Marine Park (RLFMP) in Boston’s Eastern Seaport neighborhood. The deals, which involve the conversion of office space into lab facilities, further the firms’ expertise supporting the life science sector in Boston.

“We continue to see incredible demand for life science space in Boston from leading biotech companies and we’re thrilled for them to conduct important research within the historic Innovation and Design Building,” said Steve Faber, Executive Vice President at Related Beal. “Together with Jamestown, we are serving a critical need in the life science ecosystem by providing first-class R&D space for a variety of users including small and medium sized firms allowing them to grow rapidly and execute their business plans, resulting in tomorrow’s medical breakthroughs.”

“The unique mix and dense concentration of creative and scientific firms at The IDB makes for a truly dynamic environment,” said Dana Griffin, Director of Asset Management and Development for New England at Jamestown. “These deals validate the property as a premier location for the scientific community and continue the property’s legacy as a center of innovation.”

The nine leases will bring more than 700 jobs to Boston’s Eastern Seaport neighborhood and include:

  • Entrada Therapeutics, a biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines, which leased ~81,400 square feet;
  • Shape Therapeutics, a biotech company developing RNA technologies, which leased ~36,500 square feet;
  • Jnana Therapeutics, a biotech company focused on developing best-in-class therapies to treat a wide range of diseases, which leased ~36,400 square feet;
  • Ratio Therapeutics, a discovery-stage biotechnology company developing best-in-class targeted radiotherapeutics for the treatment of cancer, which leased ~19,000 square feet;
  • Vedere Bio II, a biopharmaceutical company developing gene therapy products to restore functional vision to patients who have suffered genetic and non-genetic vision loss, which leased ~18,900 square feet;
  • Seeker Biologics, a biotech company focused on developing next generation biologics for the treatment of autoimmune, allergic, and other inflammatory diseases, which leased ~18,300 square feet;
  • Elektrofi, a biotech company focused on drug formulation and delivery innovations, which leased ~18,200 square feet;
  • Aktis Oncology, a biotech company focused on the development of a new class of targeted radiopharmaceuticals to treat a broad range of cancers, which leased ~17,900 square feet; and
  • Hotspot Therapeutics, a biotech company exploring the discovery and development of first-in-class therapies targeting nature’s regulatory sites, which leased ~17,300 square feet.

Jamestown purchased The IDB in 2013 and invested more than $200 million in the revitalization of the building. Since the announcement of Jamestown’s joint venture with Related Fund Management in 2020, the firms have invested substantially more to further enhance the property, in order to attract and retain research-based life science and creative companies. The IDB is now home to the Boston Design Center and a mix of companies including architecture and creative studios, manufacturing, research and development firms, and technology startups.

Related Beal continues to be a leading developer of laboratory and technology research space in Greater Boston. The firm has a long history of expanding and maintaining Boston’s life science presence by attracting revolutionary companies who are engaging in life-saving research and achieving medical breakthroughs. In the RLFMP, Related Beal recently completed iSQ, a 394,000 rentable square-foot, life science campus. Additional projects include South Boston’s 451 D Street, One Kenmore Square, Channelside in Fort Point, which will bring a significant mix of uses including lab, and Presidents Place in Downtown Quincy.

Jamestown is a global, design-focused real estate investment and management firm well known in the industry for its market discipline and mission of revitalizing historic spaces and emblematic buildings into mixed-use innovation hubs and community centers. In addition to The IDB, current and previous large-scale projects include Chelsea Market and the One Times Square in New York, Industry City in Brooklyn, Ponce City Market in Atlanta, Ghirardelli Square in San Francisco, and Groot Handelsgebouw in Rotterdam.


About Related Beal

Related Beal is a fully integrated real estate firm focused on development opportunities in Boston and its surrounding areas. Related Beal leverages a national real estate platform with expertise across all asset classes and storied local experience in residential, commercial, hospitality and life sciences development, property management and investment. Related Beal has developed, and is undertaking the development of, some of the most recognized buildings in the area including The Clarendon, One Back Bay, Lovejoy Wharf, The Beverly, The Quinn, Congress Square, Innovation Square, the redevelopment of Kenmore Square, and more. For more information on Related Beal, please visit

About Related Fund Management

Related Fund Management is a multi-strategy real estate investment manager that currently manages approximately $10.3 billion in commingled funds and separately managed accounts on behalf of public and private pension plans, endowments, family offices and sovereign wealth funds (estimate as of 9/30/21). RFM has a team of over 40 professionals headquartered in New York City with additional offices in Dallas, and Los Angeles. Since inception in 2010, RFM has invested across all portions of the capital stack and in all major real estate sectors.

About Jamestown

Jamestown is a global, design-focused real estate investment and management firm with a 38-year track record and mission to create places that inspire. Since its founding in 1983, Jamestown has executed transactions in excess of $35 billion. As of March 31, 2022, Jamestown has assets under management of $13.2 billion and a portfolio spanning key markets throughout the U.S., Latin America, and Europe. Jamestown employs more than 400 people worldwide with headquarters in Atlanta and Cologne, and offices in Amsterdam, Bogotá, Boston, London, Los Angeles, Madrid, Milan, New York, San Francisco, and Washington, D.C. Current and previous projects include One Times Square and Chelsea Market in New York, Industry City in Brooklyn, Ponce City Market in Atlanta, Ghirardelli Square in San Francisco, the Innovation and Design Building in Boston, and Groot Handelsgebouw in Rotterdam. For more information, visit